First published on Thursday, March 6, 2025
Last updated on Thursday, March 6, 2025
Jump to section
When you think of hazardous substances, your mind might jump to chemical factories or industrial plants. But the truth is, hazardous substances can be found in almost every workplace—from offices to construction sites, warehouses, and even schools.
If your business uses, produces, or handles any substance that could cause harm, you must carry out a Control of Substances Hazardous to Health (COSHH) risk assessment.
But what exactly qualifies as a hazardous substance covered by COSHH? Let’s break it down.
What are hazardous substances?
The HSE defines a hazardous substance as “a substance or mixture with the potential to cause harm if they are inhaled, ingested, or come into contact, or are absorbed through the skin.”
Hazardous substances covered by COSHH regulations are:
Chemicals
Products that contain chemicals
Fumes
Dusts
Vapours
Mists
Nanotechnology
Gases and asphyxiating gases
Biological agents
Germs that can cause diseases
It’s important to note that lead, asbestos or radioactive substances, while they can be hazardous and harmful, they’re not covered under COSHH and have their own regulations you must follow.
Examples of hazardous substances
Now let’s take a look at examples of hazardous substances at work and some of the possible risks to health associated with them.
Chemicals
Chemicals are probably the first thing that comes to mind when you think about a hazardous substance—and for good reason. They can be found everywhere, from industrial plants to offices. Whether it’s a strong industrial solvent or the cleaning products under the sink in the office kitchen, many chemicals have the potential to cause harm.
Common examples:
Industrial solvents (turpentine, acetone)
Acids and alkalis (sulfuric acid, sodium hydroxide)
Corrosive cleaning agents (bleach, drain cleaner)
The risks to health:
Skin burns, rashes, and irritation
Breathing difficulties from inhaling fumes
Long-term health conditions like organ damage or cancer
Products containing chemicals
Not all hazardous chemicals come in barrels labelled with hazard symbols. Many common products used in everyday tasks contain harmful substances. The risk increases when these products are sprayed, heated, or mixed with other substances.
Common examples:
Paints, varnishes, and adhesives
Pesticides and weed killers
Lubricants and degreasers
Printer toners and inks
The risks to health:
Skin irritation from frequent exposure
Toxic fumes leading to dizziness and headaches
Fire hazards—many products are flammable
Fumes
Fumes are tiny airborne particles created when a substance is burned or heated. You may not always see them, but they can cause serious harm when inhaled. Workers in welding, manufacturing, and construction are particularly at risk.
Common examples:
Welding and metalwork fumes
Plastic-melting or soldering fumes
Engine exhaust emissions
Hot tar and asphalt fumes
The risks to health:
Lung damage and respiratory illnesses
Neurological issues from heavy metal exposure
Long-term cancer risks from inhaling toxic particles
Dusts
Dust in the workplace isn’t just about cleanliness—it can be a serious health risk. Fine dust particles can be inhaled deep into the lungs, causing long-term illnesses. Some dusts, like silica for example, can be particularly dangerous.
Common examples:
Wood dust from carpentry
Silica dust from cutting bricks, tiles, or concrete
Flour dust in bakeries
Textile and cotton dust in manufacturing
The risks to health:
Occupational asthma and lung disease
Various lung cancers, nasal cancers and kidney diseases
Chronic obstructive pulmonary disease (COPD)
Skin and eye irritation
Explosive risks—some dusts can ignite under the right conditions
Vapours
Vapours are airborne chemicals released when a liquid evaporates. Many solvent-based substances give off hazardous vapours that employees inhale—often without realising it.
Common examples:
Paint, varnish, and glue vapours
Fuel vapours (petrol, diesel)
Solvent vapours (acetone, benzene)
Cleaning product fumes
The risks to health:
Dizziness, headaches, and nausea
Long-term organ damage
Fire hazards—many vapours are highly flammable
Mists
Mists form when liquids are sprayed or released under pressure, creating airborne droplets that can be inhaled.
Common examples:
Spray paint mists
Oil mists from machinery lubrication
Chemical mist from cleaning sprays
Pesticide mists in agriculture
The risks to health:
Lung damage and breathing problems
Skin and eye irritation
Ingestion risks—mist droplets can settle on food or drinks
Nanotechnology
Nanotechnology also known as nanomaterials are incredibly small particles used in high-tech industries. Because they’re so tiny, they can enter the body easily—but their long-term health effects are still unclear.
Common examples:
Carbon nanotubes (used in electronics)
Titanium dioxide nanoparticles (in sunscreens and paints)
Silver nanoparticles (antibacterial coatings)
The risks to health:
Unknown long-term health effects
Potential respiratory and organ damage
Gases and asphyxiating gases
Some gases are toxic, some are flammable, and others displace oxygen, leading to suffocation. And a leak in an enclosed space can be deadly.
Common examples:
Carbon monoxide (from faulty equipment)
Chlorine gas (used in swimming pools)
Ammonia (found in refrigeration systems)
LPG (liquefied petroleum gas)
The risks to health:
Poisoning and suffocation
Fire and explosion risks
Biological agents (Germs)
Biological agents include any naturally occurring organisms that can harm human health. While they may not seem dangerous at first, they can cause serious respiratory illnesses, allergic reactions, and infections, if there’s long-term exposure.
Workplaces that are damp, poorly ventilated, or involve water systems, soil, or animal products are at a higher risk of biological hazards.
Common examples:
Legionella bacteria in water systems (cooling towers, showers, air conditioning)
Mould spores in damp buildings or poorly ventilated areas
Fungi and bacteria in agricultural or food production settings
Animal waste in farming or veterinary work
The risks to health:
Respiratory illnesses (Legionnaires’ disease from Legionella bacteria)
Severe allergic reactions from exposure to mould or fungi
Skin infections from contaminated surfaces or animal waste
Germs that cause diseases
Unlike biological agents that exist in the environment, germs that cause diseases are primarily spread from person to person.
Viruses and bacteria can be transmitted through airborne droplets, contaminated surfaces, or bodily fluids, making them a major risk for any workplace where people are in close contact.
Common examples:
Bloodborne viruses (HIV, Hepatitis B & C)
Airborne diseases (Tuberculosis, flu, COVID-19)
Gastrointestinal infections (Norovirus, Salmonella)
The risks to health:
Severe illness or long-term health effects
Serious infections and diseases
Get help controlling hazardous substances in your workplace
By recognising the types of hazardous substances , you can ensure a more comprehensive COSHH risk assessment. Controlling exposure to these risks through elimination, engineering controls, PPE, and training is essential to protecting employee health.
Need a simpler way to manage hazardous substances? Health and safety software can make it faster and easier to complete risk assessments in line with HSE standards, store SDS data, and help you stay compliant—so you can focus on keeping your team safe!
Discover risk management from BrightSafe!